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Conference series LLC is glad to invite you to attend 16th International Conference on Proteomics, Genomics & Bioinformatics, during November 08-09, 2023 Tokyo, Japan. PROTEOMICS 2023 includes Keynote presentations, Oral talks and Poster presentation. Conference is organized with the theme "Exploring Genetic Facts for Global Health" which contains 14 Tracks to shape the theme of the conference.
Track 1: Genomics
Genomics is study of entirety of an organism's genome .Genome includes all the genes of an organism taken together plus all of the sequences and information confined therein. Genomics is a much newer field than genetics and became possible only in the former couple of decades due to technical advances in DNA sequencing and computational biology. Using High-performance computing and math practices known as Bioinformatics, genomics researchers analyse whole genome sequence data to find variants that affect health, disease or drug response.
Track 2: Human Genetics
Human genetics it is the discipline of genetic technology where study of inheritance occurs in human beings is done. Human genetics comprises a variety of overlapping fields like Genetic counselling, Genomics, Bioinformatics, Immunogenetics. Genes is the most common factor of qualities of human-inherited trait. Human genetic study can be useful as it answers about human nature, development of effective disease treatment and understand genetics of human life.
Track 3: Oncogenomics
Oncogenomics is a sub-branch of genomics. Oncogenomics is study of cancer-associated gene.it mainly focuses on Genomic, Epigenomic and Transcript Alterations. Scientists have sequenced the human genome and identified most of its genes. This genomic data is used to tackle the major health problems like cancer. Cancer is caused by accumulation of DNA mutations and epigenetic alterations leading to cell proliferation and neoplasm formation. The main goal of oncogenomics is cancer diagnosis and therapy. This can be done by identifying new tumor suppressor gene or oncogene by genomic testing.
Track 4: Medical Genetics
Medical genetics is the discipline of medicine that involves the diagnosis and management of Hereditary Disorders. Medical genetics states the application of genetics to medical care. It is a branch of genomics. It differs from human genetics which is a field of scientific research that may or may not relate to medicine. Medical genetics encompasses many different areas, including Clinical Genetics, Gene Therapy, Cytogenetics, Molecular Genetics. Diagnosis of hereditary disorders can be done by DNA Sequencing Machines, Next Generation Sequencing Machines and Prenatal Genetic Testing
Track 5: Ecogenomics
Ecogenomics is a field which deals with the application of advanced molecular technologies to study organismal response to environmental challenges in respective nature. This area studies the structure and function of nucleotide sequence isolated directly from environmental sample which is also termed as Metagenomics. Ecogenomics also covers fields like Microbial Genomics, Plant Genomics, Agrigenomics. Ecogenomics is the evolving field of Genomics.
Track 6: Genome Analysis
Genomic analysis is the identification and measurement of genomic features. DNA sequences, structural variation, gene expression are identified, measured or compared at a genomic scale. Analysis of genome requires typically High-Throughtput Sequencing or Microarray Hybridization Techniques. For analysis DNA is first sequenced, assembled, annotated and analysed. For genomic analysis few tool kits are also avalaible now. Many analysis like family-based analysis or case-control analysis can be done. Some Genome sequencing companies provide services like Protein mass spectrometry, RNA sequence analysis and many other DNA sequencing services.
Track 7: Genomics in Drug Development
Genomics, mainly Next Generation Sequencing (NGS) enables all the researchers and drug developers to understand completely the biology of the genome that drives many diseases and disorders. NGS mainly helpful for diseases like cancer. Genomics have led to development of Multi-Analyte Tumor Analysis and Targeted Therapeutics. Knowledge of human gene and their function may allow for drug discovery development process. Genetic testing for diseases lend a opportunity for development of drugs to cure diseases.
Track 8: Genome Informatics
Genome informatics is the branch of genomics in which statistical and computer techniques are applied to obtain biological information from genome sequence. Genome informatics includes several methods to analyse DNA sequence and to predict the protein sequence and structure. Informatics mainly involves the Identification of candidate genes and nucleotides for proper understanding of genetic basis of disease. It plays a role in the analysis of gene and protein expression and regulation. Genome Informatics involves Protien Mass Spectrometry, Prenatal Genetic Testing, RNA Sequence Analysis and Genome Testing.
Track 9: Application of Genomics
Next-Generation Sequencing technologies allow biomedical researchers and clinicians to increase the amount of genomic data collected on large study populations. Genomics allows the researchers to understand completely the genetic basis of drug response and disease. Genomics can be applied in many fields, including Synthetic Biology, Medicine Biotechnology, Social Sciences. Using NGS whole Genome Sequence can be identified in a single day. Genomics studies of an individual for researchers are made effortless by many Next Generation Sequencing Companies and their DNA Sequencing Services
Track 10: Genetic Toxicology
Genetic toxicology is the scientific branch which deals with the effects of physical, chemical and biological agents on the genome or heredity of living organisms. Toxic effects alter DNA directly or indirectly by induction of mutation, mistimed event activation and DNA damage. Genotoxicity can be tested by Ames Test, Micronucleus Test, SOS Test, COMET Test. Genetic toxicology testing can help narrow down the list of potential candidates by eliminating drugs that have a high cancer-causing potential.
Track 11: Toxicogenomics
Toxicogenomics is the branch of science dealing with the collection, interpretation and storage of information about protein and gene activity within the cell or tissue of an organism in response to toxic agents. Studying these mechanisms can aid in building better animal and human models, with the goal of better predicting toxic response in humans. The field of “toxicogenomics” relate global mRNA, protein and metabolite analysis related technologies to study the effects of hazards on organisms. Toxicogenomics studies of protiens can be done by protien mass spectrometry.
Track 12: Toxicogenomics Challenges & Applications
A major challenge facing investigators is to devise large-scale, high-throughput procedures for genotyping and phenotyping polymorphisms of pharmacogenetic interest as well as better ways to use this knowledge to develop risk profiles describing individual susceptibility to drugs. Toxicogenomics promises to facilitate research into toxicant mechanisms, with the opportunity of assisting in the detection of compounds with the potential to cause adverse health effects earlier in the development of pharmaceutical and chemical products.
Track 13: Pharmacogenomics
Pharmacogenomics is the research on genetic variability that influences individual response to drugs. Prescriber can individualize drug therapy by knowing patient’s genetic variation if any and can decrease chance for adverse drug reactions. Pharmaceutical companies will be able to create therapies more targeted to specific diseases, maximizing therapeutic effects while decreasing harm to nearby healthy cells. The most common variations in the human genome are called Single Nucleotide Polymorphisms. Prenatal Genetic Testing helps prescriber and geneticist to manage the therapy based on the diseases.
OMICS technology is relatively new biomarker discovery tool that can be applied to study large sets of biological molecules. Due to spectacular increase in the sensitivity, resolution and throughput of OMICS based assays its application in human observational studies has become feasible. The five most developed OMICS technologies are Genotyping, Transcriptomics, Epigenomics, Proteomics and Metabolomics.
Past Conference Report
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