Proteomics, Genomics & Bioinformatics

Cardiovascular Proteomics

Cardiovascular Proteomics

Proteomics has arrived at a critical juncture in cardiovascular research. Analyses of cardiac and vascular illness at the organ, subcellular, and molecular levels have shown dynamic, complicated, and nuanced intracellular mechanisms. Proteomic analysis' power and flexibility, which make protein separation, identification, and characterisation easier, should speed up our understanding of these processes at the protein level. Proteomics, when used correctly, gives researchers with cellular protein "inventories" at precise points in time, making it excellent for recording protein alteration as a result of a specific disease, condition, or treatment. This is performed by creating species- and tissue-specific protein databases, which serve as a foundation for future proteomic research. The advancement of proteomic techniques has allowed for a more detailed analysis of the molecular pathways behind cardiovascular illness, allowing for the discovery of both changed proteins and the type of their modification. Continued development should lead to functional proteomic studies, in which the identification of protein modification, in combination with functional data from established biochemical and physiological methods, can help us better understand how the proteome changes in response to cardiovascular disease.