Urine Metabolomics

Urine Metabolomics

Urine metabolomics emerged in response to a specific disease or therapeutic intervention for the discovery of non-invasive biomarkers that can detect small metabolic abnormalities. Urine is distinguished from other biofluids by its ease of collection, abundance of metabolites, and capacity to reflect abnormalities in all metabolic pathways within the body. To quench any biogenic and/or non-biogenic chemical processes, urine samples for metabolomic analysis must be quickly refrigerated. Because of the constant advances in its linked technologies, liquid chromatography (LC)-MS is without a doubt the most analytical technique used in urine metabolomics. The Urine Metabolome database includes detailed information on 3100 small molecule metabolites discovered in human urine, as well as 3900 concentration values. The metabolite data columns have hyperlinks to other databases (KEGG, PubChem, ChEBI, Chemspider, DrugBank, PDB and Uniprot). Chemical, clinical, and molecular/biochemistry data are all used to create this information.

 

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